Clinxa / Clinxa-A Gel

Clinxa / Clinxa-A Gel

Product Description

Composition:  Clindamycin Phosphate 1 % Adapalene 0.1 % Allantoin Base

Description: Clindamycin phosphate 1% and Adapalene 0.1% Gel is an antibiotic and retinoid combination gel product with two active ingredients. Clindamycin phosphate is a water-soluble ester of the semi-synthetic antibiotic produced by a 7(S)- Chloro-substitution of the 7(R)-hydroxyl group of the parent antibiotic Lincomycin.

 

Mechanism of Action:

Clindamycinbinds to the 50S ribosomal subunits of susceptible bacteria and prevents elongation of peptide chains by interfering with peplidyl transfer, thereby suppressing bacterial protein synthesis.

Adapaleneacts on retinoid receptors. Biochemical and pharmacological profile studies have demonstrated that Adapalene is a modulator of cellular differentiation, keratinization, and inflammatory processes all of which represent important features in the pathology of acne vulgaris. Adapalene normalizes the differentiation of follicular epithelial cells resulting in decreased micro-comedone formation.

 

Indications and Usage: Indicated for the topical treatment of acne vulgaris (in cases of severe acne). At bedtime, squeeze a pea-sized amount of medication onto one fingertip. Dot onto the chin, cheeks. nose, and forehead, then gently rub over the entire face and should be kept away from the eyes, mouth, angles of the nose, and mucous membranes.

 

Side Effects: The most common dermatological adverse effects seen are such aserythema, scaling, itching, burning, and stinging.

 

Drug Interactions:  Concomitant topical medication, medicated or abrasive soaps and cleansers, soaps and cosmeticserythromycin-containing products, neuromuscular blocking agents

 

Storage Condition: Store below 250 C (77CF) & to protect from light.

 

Pack: 20gm Tube.


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